St. Francis Is First Hospital in Nation to Enroll Patient in Major Study to Enhance Stent Placement
Roslyn, NY, July 9, 2018- As a former water department inspector, 74-year-old Bogdan Karas can truly appreciate the benefits of good plumbing. So when the Vietnam army veteran was asked to take part in a global study that could change the path of treating clogged arteries, he volunteered immediately. The major clinical trial will evaluate the superiority of a light-based, 3-D imaging system called optical coherence tomography or OCT compared to traditional X-ray-based angiography in patients with complex coronary artery disease who receive a stent.
The ILUMIEN IV trial, sponsored by Abbott, will evaluate long-term outcomes of patients who undergo stent implantation guided by OCT versus X-ray. It is the first large-scale randomized global study using OCT imaging in patients with high-risk coronary artery disease. During OCT-guided stent placement, physicians use high-resolution images taken directly inside the patient's vessels to accurately measure dimension and choose a stent that best fits the vessel. OCT is also used to help physicians ensure the stent is fully expanded and is flush against a vessel wall for better patient outcomes.
The trial will enroll up to 3,650 patients at 125 centers in North America, Europe, and Asia to determine if OCT-guided stent procedures result in larger vessel diameters — thus, allowing increased blood flow and improved outcomes. Patients with complex disease may have multiple, or totally blocked arteries, or other diseases such as diabetes; and these patients currently account for an increasing number of cases.
"We are very excited to be evaluating this new technology in what could change the way we diagnose and treat coronary artery disease,” says Richard Shlofmitz, M.D., Chairman of Cardiology at St. Francis. “Most of the world is still relying on angiography for stent placement using a two-dimensional view. Having a 3D perspective of the inside and outside of coronary arteries is a real game changer.”
“Only a small fraction of hospitals use OCT on a regular basis and St. Francis is at the forefront of integrating this technology into routine practice,” says Allen Jeremias, M.D., Co-Principal Investigator. “We’re always grateful to patients who participate in clinical studies that help us to advance the field of Medicine. I am convinced that this study in particular will lead to greater accuracy and precision in the treatment of coronary artery disease.
“I feel great, and am breathing a lot easier,” says Karas, an avid soccer fan who considers enrolling in the study a winning goal.
Contact: Rosemary Gomez, 516-563-7965, firstname.lastname@example.org