Heart Failure Research Protocols

   Title of Study                                                          Principal Investigator

INTELLECT 2-HF : Investigation to Optimize Hemodynamic Management of HeartMate II™ Left Ventricular Assist Device Patients using the CardioMEMS™ Pulmonary Artery Pressure Sensor in Advanced Heart Failure

Rita Jermyn, MD

Hemodynamic Guided Monitoring In Heart Failure (GUIDE HF)

Rita Jermyn, MD

Optimization of Cardiac Pacing Using CardioMEMS

Rita Jermyn, MD

PRESERVED-HF: Effects of Dapagliflozin on Biomarkers, Symptoms and Functional Status in Patients with Preserved Ejection Fraction Heart Failure

Rita Jermyn, MD

EMBRACE-HF : Empagliflozin evaluation by measuring impact on Hemodynamics in patients with Diabetes and Heart Failure

Rita Jermyn, MD

DEFINE-HF Dapagliflozin Effect on symptoms and biomarkers iN diabetEs patients with Heart Failure

Rita Jermyn, MD

Barostim Neo - Baroreflex Activation Therapy for Heart Failure

Rita Jermyn, MD

Recent publications in the area of Heart Failure research 

Wolfson A, Saxon L, Shavelle D, Jermyn R. Baseline diastolic pressure gradient and pressure reduction in chronic heart failure patients implanted with the CardioMEMS HF sensor. ESC Heart Fail. 2018 Jun; 5(3): 316–321. 

Desai A, Bhimaraj A, Bharmi R, Jermyn R Et al. Reduction in Heart Failure Hospitalizations with Ambulatory Hemodynamic Monitoring Seen in Clinical Trials Is Maintained in the “Real World” JACC March 2017. 

Jermyn R, Alam A, Kvasic J, et al. Hemodynamic guided heart failure management using a wireless implantable sensor: Infrastructure, methods, and results in a community heart failure disease management program Clinical Cardiology. 2017; 40:170–176.  

Heywood JT, Jermyn R, Abraham WT et al. Generalizability of Hemodynamic Guided Heart Failure Management Using a Permanently Implanted Pulmonary Artery Pressure Sensor: Initial Clinical Experience in the First 2000 Patients Managed for 6 Months Circulation. 2017 Apr 18;135(16):1509-1517.

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